John P Lydon Selected Research

Progesterone

1/2021	Illuminating the "Black Box" of Progesterone-Dependent Embryo Implantation Using Engineered Mice.
12/2020	Targeting progesterone signaling prevents metastatic ovarian cancer.
10/2020	Pten and Dicer1 loss in the mouse uterus causes poorly differentiated endometrial adenocarcinoma.
1/2019	Impaired Progesterone-Responsiveness of CD11c+ Dendritic Cells Affects the Generation of CD4+ Regulatory T Cells and Is Associated With Intrauterine Growth Restriction in Mice.
1/2018	Human endometrial stromal cell decidualization requires transcriptional reprogramming by PLZF.
12/2017	PR-Set7 deficiency limits uterine epithelial population growth hampering postnatal gland formation in mice.
1/2017	Growth regulation by estrogen in breast cancer 1 (GREB1) is a novel progesterone-responsive gene required for human endometrial stromal decidualization.
10/2016	A Gata2-Dependent Transcription Network Regulates Uterine Progesterone Responsiveness and Endometrial Function.
4/2016	The Promyelocytic Leukemia Zinc Finger Transcription Factor Is Critical for Human Endometrial Stromal Cell Decidualization.
4/2015	Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation.

For more, sign up at right for free...

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

John P Lydon Research Topics

Disease

28	Neoplasms (Cancer) 01/2022 - 01/2002
12	Endometriosis 01/2022 - 09/2004
11	Endometrial Neoplasms (Endometrial Cancer) 01/2022 - 06/2007
10	Carcinogenesis 11/2019 - 01/2002
10	Breast Neoplasms (Breast Cancer) 01/2017 - 01/2002
9	Infertility (Sterility) 01/2021 - 01/2010
8	Female Infertility 01/2021 - 01/2002
6	Hyperplasia 01/2017 - 08/2003
4	Neoplasm Metastasis (Metastasis) 12/2020 - 01/2011
4	Inflammation (Inflammations) 01/2020 - 10/2012
3	Ovarian Neoplasms (Ovarian Cancer) 12/2020 - 09/2014
3	Adenocarcinoma 10/2020 - 05/2009
3	Fetal Growth Retardation (Intrauterine Growth Retardation) 01/2019 - 08/2013
3	Leukemia 01/2019 - 04/2016
3	Metaplasia 03/2016 - 04/2011
2	Endometrial Hyperplasia 01/2021 - 08/2013
2	Spontaneous Abortion (Miscarriage) 01/2018 - 08/2008
2	Premature Birth (Birth, Premature) 12/2017 - 06/2012
2	Prostatic Neoplasms (Prostate Cancer) 10/2016 - 07/2016
2	Endometrioid Carcinoma 03/2016 - 01/2010
2	Uterine Diseases (Endometrial Disease) 01/2010 - 05/2009
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2021
1	Carcinoma (Carcinomatosis) 12/2020
1	Fibrosis (Cirrhosis) 10/2020
1	Clear Cell Adenocarcinoma 10/2020
1	GATA2 Deficiency 10/2016
1	Testicular Neoplasms (Testicular Cancer) 10/2016
1	Multiple Abnormalities 02/2016
1	Cysts 01/2016
1	Salivary Gland Neoplasms (Salivary Gland Cancer) 01/2015
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 09/2014
1	Thymoma (Thymic Carcinoma) 05/2014
1	Hypersensitivity (Allergy) 01/2014
1	Uterine Cervical Neoplasms (Cancer of the Cervix) 11/2013
1	Adenomyosis 10/2013
1	Rare Diseases (Rare Disease) 09/2013
1	Lymphangioleiomyomatosis (Lymphangiomyomatosis) 09/2013
1	Leiomyoma (Uterine Fibroids) 09/2013

Drug/Important Bio-Agent (IBA)

23	Progesterone FDA LinkGeneric 01/2021 - 01/2002
21	Progesterone Receptors (Progesterone Receptor)IBA 01/2021 - 01/2002
15	Hormones (Hormone)IBA 01/2021 - 04/2003
9	Estrogens (Estrogen)FDA Link 01/2017 - 01/2010
8	SteroidsIBA 09/2015 - 01/2002
6	Fumigant 93 (D-D)IBA 02/2016 - 05/2009
5	Proteins (Proteins, Gene)FDA Link 01/2021 - 09/2015
5	Protein Isoforms (Isoforms)IBA 10/2020 - 01/2002
5	CateninsIBA 03/2016 - 08/2011
4	LigandsIBA 11/2019 - 08/2012
4	Phenobarbital (Luminal)FDA Link 11/2018 - 05/2010
4	Progestins (Progestagens)IBA 06/2012 - 08/2003
3	TensinsIBA 01/2022 - 01/2017
3	Transcription Factors (Transcription Factor)IBA 10/2020 - 04/2016
3	Messenger RNA (mRNA)IBA 10/2020 - 03/2016
3	MicroRNAs (MicroRNA)IBA 10/2020 - 07/2008
3	Estrogen ReceptorsIBA 11/2015 - 11/2013
2	Phosphoric Monoester Hydrolases (Phosphatases)IBA 01/2022 - 01/2017
2	Keratin-5 (Keratin 5)IBA 01/2021 - 01/2019
2	Estradiol (Delestrogen)FDA LinkGeneric 01/2021 - 09/2004
2	Mifepristone (RU 486)FDA Link 12/2020 - 10/2020
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2020 - 06/2012
2	GonadotropinsIBA 01/2020 - 03/2008
2	Cre recombinaseIBA 01/2018 - 01/2017
2	Transforming Growth Factor-beta Type I ReceptorIBA 01/2018 - 01/2017
2	Doxycycline (Periostat)FDA LinkGeneric 01/2017 - 08/2011
2	Progesterone CongenersIBA 11/2013 - 08/2012
1	Polycomb Repressive Complex 2IBA 01/2022
1	Enhancer of Zeste Homolog 2 ProteinIBA 01/2022
1	Cyclin-Dependent Kinase Inhibitor p16IBA 01/2021
1	A-factor (Streptomyces)IBA 12/2020
1	LactoferrinIBA 10/2020
1	PTEN Phosphohydrolase (PTEN Phosphatase)IBA 10/2020
1	EndoribonucleasesIBA 10/2020
1	Lim KinasesIBA 10/2020
1	Hepatocyte Nuclear Factor 1IBA 10/2020
1	EphrinsIBA 10/2020
1	Transforming Growth Factor beta (TGF-beta)IBA 10/2020
1	Keratins (Keratin)IBA 11/2019
1	Nuclear Receptor Coactivator 2IBA 01/2018
1	ChemokinesIBA 01/2017
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2017
1	ChromatinIBA 10/2016
1	Biomarkers (Surrogate Marker)IBA 10/2016
1	AntigensIBA 10/2016
1	GATA Transcription FactorsIBA 07/2016
1	Androgen Receptors (Androgen Receptor)IBA 07/2016
1	Steroidogenic Factor 1IBA 05/2016
1	glucose-regulated proteinsIBA 03/2016
1	InflammasomesIBA 11/2015
1	CytokinesIBA 01/2015
1	Tamoxifen FDA LinkGeneric 05/2014
1	MK 2206IBA 05/2014
1	Deoxyglucose (2 Deoxy D glucose)IBA 12/2013
1	Medroxyprogesterone Acetate (Depo-Provera)FDA LinkGeneric 11/2013
1	Cadherins (E-Cadherin)IBA 10/2013
1	lipoarabinomannan (LAM)IBA 09/2013

Therapy/Procedure

10	Therapeutics 01/2022 - 07/2009
1	Drug Therapy (Chemotherapy) 01/2022
1	Immunotherapy 10/2016
1	Autologous Transplantation 05/2016
1	Molecular Targeted Therapy 01/2015